Peripheral Neuropathy in Krabbe’s Disease

Peripheral neuropathy in Parkinson's disease.

BACKGROUND Recent studies suggest an increased frequency of peripheral neuropathy (PN) in Parkinson's disease patients (PD) (Toth et al. 2010). The aim of our study is to verify the increased frequency of PN in our group of PD patients compared to an age-matched control group. We sorted patients according to the duration of L-DOPA treatment, L-DOPA dosage, and age below or over 50 years. METH...

Prevalence of Peripheral Neuropathy in Diabetic Patients

Abstract Objective: Diabetic peripheral neuropathy is the main risk factor of diabetic foot ulcer and its early diagnosis is important to prevent limb amputation. We assessed the prevalence of peripheral neuropathy in diabetic patients. Materials and methods: This cross-sectional study was performed on 352 randomly selected diabetic patients using a standardized questionnaire including age, g...

Parkinson’s Disease and Peripheral Neuropathy

Creutzfeldt-Jakob disease associated with peripheral neuropathy.

We describe the case of a patient with sporadic Creutzfeldt-Jakob disease (sCJD) with associated peripheral neuropathy and discuss the literature on this topic. A patient with autopsy proven CJD presented with the clinical signs of a sensory (large fibres) polyneuropathy. The neurophysiologic study showed a sensory-motor polyneuropathy with predominant axonal pattern, without denervation signs....

Familial extrapyramidal disease with peripheral neuropathy.

A family is presented in which 10 members over three generations developed a Parkinsonian syndrome. Two siblings had additional clinical and electrophysiological evidence of an associated peripheral neuropathy and sural nerve biopsy in one case revealed axonal loss. This is the third family reported in the literature in which an extrapyramidal syndrome is associated with neuropathy, but differs...